Asia Minor, the land area of modern-day Turkey, was initially settled by the Hatti people between 2500 and 2000 BC. Toward the end of that period, the Indo-European Hittites, drawn to the mild climate, began a slow settlement alongside the indigenous Hattis, mixing peaceably with them. By 1750 BC, the Hittites had become the dominant people group.

In the twelfth century BC the Hittites fell to the Sea Peoples. They developed coastal cities along the Aegean, which by the eighth century were conquered by the Greeks. The Lydian king Croesus came to power in 560 BC in Sardis and subdued the Greeks, only to fall in 546 BC to Cyrus of Persia. In 334 333 BC Alexander the Great defeated the Persians in two key battles and won Asia Minor. After Alexander’s death, one of his generals, Seleucus, took over. Then, in 190 BC the Romans defeated the Seleucids and assumed control. This inaugurated an extended period of peace, during which time Jewish communities of the Diaspora settled throughout the region.

The missionary journeys of the apostle Paul (Saul of Tarsus) took him into and around much of Asia Minor, and directly or indirectly he was responsible for the establishment of most of the first-century churches there. The following cities of Asia Minor are mentioned in the NT.

Eastern Mediterranean

Tarsus. The birthplace of the apostle Paul (Acts 9:11; 21:39; 22:3), Tarsus is located on the Mediterranean coast, nine miles northeast of modern-day Mersin. Tarsus became the capital of the Roman province of Cilicia in 67 BC. Cleopatra and Mark Antony met and built their fleet in this grand city. When his life was threatened after his conversion, Paul was sent to Tarsus from Jerusalem (9:30).

Antioch. Antioch (Antakya) is located just inland from the Mediterranean coast, on the east bank of the Orontes River. Jewish and Gentile believers who fled Jerusalem after the death of Stephen planted a church here, where followers of Jesus were first called “Christians.” Barnabas brought Saul from Tarsus to Antioch, where they labored together for a year, teaching the church, prior to setting off on their first missionary journey (Acts 11:19–30). Paul later returned, along with Silas, bearing the requirements for Gentile believers from the Jerusalem council (15:22–35).

Southern Ports

Seleucia. Known today as Samandağ, Seleucia was Antioch’s port, the place from which Saul, Barnabas, and John Mark embarked on their first missionary journey in AD 47 (Acts 13:4).

Perga in Pamphylia. Perga is just east of Antalya on the southern Mediterranean coast. Archimedes’ student Apollonius the mathematician lived here in the late third century BC. On their first missionary journey, Paul and Barnabas disembarked in Perga for destinations in southwestern Asia Minor, while John Mark left them to return to Jerusalem (Acts 13:13–14). On their return trip of the same journey, Paul and Barnabas stopped in Perga again, this time preaching before heading to Attalia (14:25).

Galatia

The following cities became part of the politically defined Roman province of Galatia in 25 BC. They are to be distinguished from ethnic Galatia, which is a region farther north, around modern-day Ankara.

Pisidian Antioch. Modern Yalvaç, or Pisidian Antioch, is northeast of Isparta in the lake region. On their first missionary journey, Paul and Barnabas preached in the synagogue here and generated enormous interest in the gospel (Acts 13:14–43). The following Sabbath, nearly the entire city came out to listen to them. Jealous Jewish leaders incited a persecution, causing Paul and Barnabas to reorient their ministry to Gentiles and then leave the region for Iconium (13:26–51). They returned on their way back to Antioch to strengthen the disciples and appoint elders (14:21–23).

Iconium. Iconium, today called Konya, is about sixty-five miles southeast of Pisidian Antioch. It is one of the most ancient settlements of the region, dating to the third millennium BC. Paul and Barnabas preached in the synagogue here on their first missionary journey, initially winning Jewish and Gentile converts but angering other Jews. Paul and Barnabas eventually feared for their safety and escaped to Lystra and Derbe (Acts 14:1–6). However, they came back on the return trip to Antioch (14:21–23).

Lystra. Frequently mentioned with Derbe (Acts 14:6; 16:1), Lystra (modern Hatunsaray) is nineteen miles south of Iconium. Paul and Barnabas fled here from Iconium and preached. Paul healed a lame man, and as a result he and Barnabas were presumed by the enthusiastic crowd to be Zeus and Hermes. At the instigation of Paul’s Jewish opponents, the crowd’s sentiments turned, and Paul was nearly stoned to death. He and Barnabas left for Derbe the following day (14:6–20), but they came back on their return trip (14:21–23). Paul returned on his second missionary journey, where he met his protégé, Timothy (16:1–2).

Derbe. About fifty miles southeast of Lystra and slightly north of present-day Karaman is Derbe. Paul and Barnabas fled here after Paul’s stoning in Lystra on their first missionary journey, preached the gospel, made many disciples, and appointed elders (Acts 14:21–23). Among the disciples likely was Gaius, who later accompanied Paul during his third missionary journey (20:4).

Western Aegean Ports

Troas. Troas was a major northwest seaport located about twelve miles southwest of Troy. On his second missionary journey, Paul, traveling with Silas and Timothy, was prevented from entering Bithynia by the Spirit of Christ and went instead to Troas. Here he had a vision beckoning him to Macedonia, which he promptly obeyed (Acts 16:6–11). Because this is the first of the so-called “we” passages in Acts, Luke may have joined the group here (16:10). Paul also stopped at Troas on the return to Jerusalem from his third missionary journey. There he raised Eutychus after the latter’s traumatic fall (20:4–12). Troas is mentioned twice more, suggesting that Paul spent time here in addition to the above visits (2 Cor. 2:12–13; 2 Tim. 4:13).

Adramyttium. A few miles south of Troas was the port of Adramyttium. It was the origin of the ship that transported Paul from Caesarea to Myra around AD 60 en route to Rome (Acts 27:2).

Assos. Assos is an acropolis sitting 774 feet above sea level, up from the village of Behramkale. It overlooks the Bay of Edremit and has a splendid view of Lesbos. Doric columns from the seventh-century BC temple of Athena are prominent at the site. According to Acts 20:13–14, on his return from his third missionary journey, Paul went overland from Troas to Assos, and there he joined his traveling companions on their ship. From here on the way to Miletus, they made several nearby island stops off the coast of Asia Minor: Mitylene on Lesbos, Chios, and Samos (20:14–16).

Miletus. Located about twenty miles south of Ephesus, at the point where the Meander River met the Gulf of Latmus (now silted over), was the important southwestern seaport of Miletus. The city was significant in the NT era for its four harbors. A center for commerce, scholarship, geometry, and science, it was also the prototype for principles of city planning later applied throughout the Roman Empire. On his third missionary journey, Paul’s farewell to the Ephesian elders took place here (Acts 20:15–38). Later he left the ill Trophimus in Miletus (2 Tim. 4:20).

Southwestern Ports

Patara. Sitting on the Mediterranean coast at the mouth of the Xanthus River, about forty miles west of present-day Demre, Patara was a flourishing harbor and commercial center in antiquity. Paul changed ships here as he returned to Jerusalem from his third missionary journey, after island stops in Kos and Rhodes (Acts 21:1–2).

Myra. Myra is a coastal ruin due south of present-day Demre. In the NT era, the seaport featured a Roman theater, Roman baths, and two rock-cut necropolises. Here, Paul changed ships around AD 60 on his way to Rome while in the custody of a centurion (Acts 27:5).

Cnidus. At the tip of the long, narrow Datca peninsula on the extreme southwestern corner of Asia Minor lies Cnidus. Founded around 360 BC, the acropolis rises one thousand feet above sea level. The port included two harbors and four theaters but was most famous for its fourth-century BC statue of Aphrodite, carved by the Athenian sculptor Praxiteles. Around AD 60 the ship carrying Paul to Rome stopped here because of slow winds and changed course (Acts 27:7).

Seven Churches of Revelation; Lycus Valley

The seven churches of Rev. 1–3 lay along a north-south elliptical route in western Asia Minor. Laodicea, the seventh, forms a tight geographic triangle with Hierapolis and Colossae in the Lycus Valley.

Ephesus. Known today as Selçuk, ancient Ephesus is located on the Aegean coast of Asia Minor at the mouth of the Cayster River. It was founded in the eleventh century BC by the Ionians and later ruled successively by the Athenians, Spartans, Persians, and Greeks. Roman governance began in 190 BC. Later, Ephesus became the capital of the province of Asia, as well as its most important commercial center. During the NT era, the Artemision (see Artemis) was an important pilgrimage site.

Paul stopped in Ephesus briefly on his second missionary journey, leaving Priscilla and Aquila. They later encountered and mentored Apollos there (Acts 18:19–26). On his third journey, Paul remained in Ephesus for three years, teaching, performing miracles, and healing the sick (19:1–22) until the riot incited by Demetrius the silversmith (20:1). He wrote 1 Corinthians in Ephesus (1 Cor. 16:8) and later wrote to the Ephesians from his Roman prison cell (Eph. 3:1) as well as to Timothy in Ephesus (1 Tim. 1:3).

In Rev. 2:1–7 the Ephesian church is commended for its perseverance but chastised for having lost its first love.

Smyrna. Smyrna (modern İzmir) is located about thirty-five miles north along the coast from Ephesus. In 195 BC it became the first city in Asia Minor to erect a temple for the imperial cult, and by the next century it was known as “the ornament of Asia.” In its letter, which mentions no negatives, the church is encouraged to be faithful in its suffering (Rev. 2:8–11).

Pergamum. About seventy miles north of Smyrna is Pergamum (modern Bergama). The dazzling acropolis sits one thousand feet high and about sixteen miles inland from the Aegean. The Attalids, who ruled 263–133 BC, allied Pergamum with Rome and built it into a major religious and intellectual center, constructing the great altar to Zeus Soter, the temple to Athena Nicephorus, and the large complex dedicated to Asclepius Soter. They also established a ruler cult and built a library containing two hundred thousand volumes, which at its peak was second only to the library at Alexandria.

The letter to the church (Rev. 2:12–17) references Satan’s throne, which many believe to be a reference to the altar to Zeus. The church is commended for its faithfulness and yet is admonished for tolerating those advocating pagan practices within the community.

Thyatira. Thyatira (now called Akhisar) is about thirty-five miles southeast of Pergamum. It was mainly noted as having a significant concentration of trade guilds, especially those connected with textiles. Lydia, Paul’s disciple and host in Philippi, was a dealer in purple cloth from Thyatira (Acts 16:14). The church is commended for its good deeds but criticized for tolerating the false teacher Jezebel (Rev. 2:18–29).

Sardis. Forty-five miles east of Smyrna, on the banks of the Pactolus, is Sardis, where Croesus, the sixth-century BC Lydian king, was said to have panned for gold. He also built an impressive Ionic temple to Artemis here. The letter to Sardis is a stern warning to wake up, highlighting the church’s incomplete deeds and impurity (Rev. 3:1–6).

Philadelphia. Philadelphia (modern Alaşehir) is twenty-six miles southwest of Sardis on the Cogamis River. The city was noted for its wine production, and it was nicknamed “Little Athens” during the Roman era. Its letter is thoroughly positive; the church is commended for its deeds and faithfulness (Rev. 3:7–13).

Laodicea. Laodicea is located about a hundred miles east of Ephesus, in a valley where the Lycus River joins the Meander; Hierapolis is just to the north, and Colossae just to the east. Laodicea was founded in the third century BC by the Seleucid king Antiochus II, who named it after his wife. Cicero served as proconsul there in 51 BC.

Laodicea was a prosperous city, a center for banking, eye salve (“Phrygian powder”), and wool production. Its water was supplied via aqueducts from Hierapolis’s hot springs, but it arrived lukewarm and heavy with mineral impurities—no match for either its hot source or Colossae’s cold springs. The Laodicean letter employs all of this background in its harsh message to the church, which it describes as tepid, poor, blind, and naked (Rev. 3:14–22).

Hierapolis. Eight miles to the north of Laodicea, Hierapolis sits atop dramatic white cliffs created by its hot springs (Col. 4:13). The city was home to the reputed entrance to the underworld, the Plutonium, and had an enormous necropolis.

Colossae. Colossae, ten miles east of Laodicea, was a center for dyed red wool. Although wealthy in the late fourth century BC, it was later eclipsed by Laodicea.

The churches in Laodicea, Hierapolis, and Colossae (the oldest of the three cities) were begun by Epaphras and shared letters, including Paul’s letter to the Colossians (Col. 4:13–16). The slave Onesimus carried it, along with the Letter to Philemon, to Colossae, where Philemon hosted the house church (Col. 4:9; Philem. 10–12).