There seems to be little connection between the Greek's request and Jesus' response until you begin to speculate about why this leap in logic. Something appears to be missing. Why does Jesus seemingly ignore the Greeks request for an audience with him?
Jesus knows that the Greeks "Seek Wisdom" and are only interested in debate and dialogue on theological philosophical issues of the day. Even if they are God Fearers they are perhaps noncommittal. Jesus draws a line in the sand now that this is Passion Week and, in effect says, the time for debating is over! Those who would be my disciples must lose their life and hate their life in this world in order to save it. Unless a kernel of wheat falls into the ground and dies, it remains only a single seed. But if it dies, it produces many seeds. …